Negative Expression Values after Background Substraction

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Negative Expression Values after Background Substraction

Postby nharper83 » Oct 31 2011 11:51 am

My lab has been working on micro arrays. The arrays we are using have approximately 47K probes. After subtraction of background noise, there are about 8,500 probes that don't have any negative values. I was wondering if this is normal and if anyone had any suggestions on how to handle these negative values.

Thanks.
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