Stimulation of monocytes/DCs with cytokines and danger sigs

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Stimulation of monocytes/DCs with cytokines and danger sigs

Postby Whelans2 » Aug 11 2016 6:04 pm

I am interested in looking at the modulation of ligands by treating monocytes and DCs with pro and anti-tumor cytokines, as well as Danger signals (alone or in combo).

I am currently thinking of cytokines, IL-12, IFN-Y, GMCSF, and then also HSP-60/70. sting agonist, HMGB1, ATP and URIC acid and S100s. Any one have any ideas for good combos and mono treatments?
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